D-norvaline, N-[(phenylmethoxy)carbonyl]-
N-[(benzyloxy)carbonyl]-D-norvaline
CAS: 42918-89-8
Molecular Formula: C13H17NO4
D-norvaline, N-[(phenylmethoxy)carbonyl]- - Names and Identifiers
| Name | N-[(benzyloxy)carbonyl]-D-norvaline |
| Synonyms | Z-D-NVA-OH Z-D-Nva-OH Z-D-NORVALINE Z-D-APE(2)-OH Cbz-D-norvaline RARECHEM AL CF 0967 N-ALPHA-CBZ-D-NORVALINE Z-D-NHCH[CH3(CH2)2]-COOH N-ALPHA-CARBOBENZOXY-D-NORVALINE N-[(Benzyloxy)carbonyl]-D-norvaline N-[(benzyloxy)carbonyl]-D-norvaline D-norvaline, N-[(phenylmethoxy)carbonyl]- N-ALPHA-CARBOBENZOXY-D-2-AMINO PENTANOIC ACID (2R)-2-{[(Benzyloxy)carbonyl]amino}pentanoic acid |
| CAS | 42918-89-8 |
| InChI | InChI=1/C13H17NO4/c1-2-6-11(12(15)16)14-13(17)18-9-10-7-4-3-5-8-10/h3-5,7-8,11H,2,6,9H2,1H3,(H,14,17)(H,15,16)/t11-/m1/s1 |
D-norvaline, N-[(phenylmethoxy)carbonyl]- - Physico-chemical Properties
| Molecular Formula | C13H17NO4 |
| Molar Mass | 251.28 |
| Density | 1.184±0.06 g/cm3(Predicted) |
| Melting Point | 89.5-90℃ (ethyl acetate ligroine ) |
| Boling Point | 439.4±38.0 °C(Predicted) |
| Flash Point | 219.568°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Powder |
| Color | White |
| pKa | 4.00±0.20(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.533 |
D-norvaline, N-[(phenylmethoxy)carbonyl]- - Introduction
N-[(benzyloxy)carbonyl]-D-norvaline is a compound also known as N-[(benzyloxy)carbonyl]-D-norvaline. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- N-[(benzyloxy)carbonyl]-D-norvaline is a white crystalline solid.
-It is an amino acid derivative consisting of D-norvaline and benzyl carboxylic acid (benzyloxycarbonyl).
-It has good solubility at room temperature and is soluble in alcohol solvents and organic solvents.
Use:
- N-[(benzyloxy)carbonyl]-D-norvaline are commonly used as starting materials or intermediates in pharmaceutical synthesis and organic chemical reactions.
-It can be used to synthesize anticancer drugs, antiviral drugs, hormone drugs, etc.
Preparation Method:
The preparation method of-N-[(benzyloxy)carbonyl]-D-norvaline includes synthesis and purification steps.
-Synthesis step Generally, starting from D-norvaline, it is first protected as benzyl chloride (benzyloxycarbonyl chloride), then reacted with an appropriate base to obtain N-benzyl-D-norvaline, and finally deprotected to obtain the target product.
Safety Information:
- N-[(benzyloxy)carbonyl]-D-norvaline specific hazard information has not been reported in detail.
-When handling and using it, it is recommended to follow the usual laboratory safety procedures and personal protective measures.
-avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
Please note that the above information is for reference only and should be used in accordance with relevant regulations and laboratory safety standards.
Nature:
- N-[(benzyloxy)carbonyl]-D-norvaline is a white crystalline solid.
-It is an amino acid derivative consisting of D-norvaline and benzyl carboxylic acid (benzyloxycarbonyl).
-It has good solubility at room temperature and is soluble in alcohol solvents and organic solvents.
Use:
- N-[(benzyloxy)carbonyl]-D-norvaline are commonly used as starting materials or intermediates in pharmaceutical synthesis and organic chemical reactions.
-It can be used to synthesize anticancer drugs, antiviral drugs, hormone drugs, etc.
Preparation Method:
The preparation method of-N-[(benzyloxy)carbonyl]-D-norvaline includes synthesis and purification steps.
-Synthesis step Generally, starting from D-norvaline, it is first protected as benzyl chloride (benzyloxycarbonyl chloride), then reacted with an appropriate base to obtain N-benzyl-D-norvaline, and finally deprotected to obtain the target product.
Safety Information:
- N-[(benzyloxy)carbonyl]-D-norvaline specific hazard information has not been reported in detail.
-When handling and using it, it is recommended to follow the usual laboratory safety procedures and personal protective measures.
-avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
Please note that the above information is for reference only and should be used in accordance with relevant regulations and laboratory safety standards.
Last Update：2024-04-09 15:17:57
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